This course provides an overview of ethical principles relevant to the design of trials involving human subjects. Learners will review foundational study designs and design tools with a focus on ethical and regulatory considerations.Topics include:Differentiating between research and quality improvement.Observational and interventional designs.Randomization, blinding, and placebos.First-in-Human, or Phase I, trials.Cluster randomization.Comparative effectiveness research.There was no commercial...

This course provides an overview of ethical concerns regarding conflicts of interest in biomedical research. It also offers several approaches to safeguarding against conflicts of interest and describes related federal policies. Intended primarily for researchers, the course:Explains what a conflict of interest is and why conflicts are problematic.Provides data and analysis regarding the extent of conflicts of interest in research.Assesses strategies for avoiding and remediating conflicts of interest.Describes...

The goal of this activity is to provide learners with basic knowledge and skills on how to make ethical evaluations on research protocols, including understanding of specific ethical requirements and regulations. In this activity, learners will engage with the content by moving through a series of website pages that other brief lecture videos, links to related readings, downloadable resources, and quizzes.There was no commercial support used in the development of this educational activity.Content...